Unlike bio-inert ceramics (alumina, zircon), tricalcic phosphate ceramics are bio-active and create chemical exchanges with living tissue.
After insertion, the material is the locus of extra-cellular dissolution and degradation of cellular origin.
These physical-chemical phenomena depend on the chemical (hydroxyapatite, beta tricalcic phosphate) and physical structure (size and diameter of the material’s pores) and its environment.
The biological fluids in the pores are enriched with calcium, causing the precipitation of hydroxyapatite crystals similar to those in the neighbouring bone (a calcification not an ossification process).If the macropores are of sufficient size, osteoconduction processes can come into play as well as subsequent Haversian bone remodelling.
Tricalcic phosphate ceramics are osteoconductive and require intimate contact with the receiving bone and no movement between the bone and the implant.
TRIHA+ tricalcic phosphate is highly soluble and degrades quite rapidly in vivo.

Use :

- In orthopaedics: filling in bone losses from the base of the acetabulum, replacing hip prostheses, etc..
- In maxillo-facial operations: filling cysts, periodontal pockets, facial osteoplasties, supplements to dental implants, etc.