Project Description

TRIHA+®

Synthetic Bone Substitute

TRIHA+® is a synthetic monophasic ceramic made of tricalcium phosphate (TCP).
Tricalcium phosphate Ca3(PO4)2 provides excellent osteointegration of the ceramic.
TRIHA+® is biocompatible and safe.

ADVANTAGES

  • Biocompatible
  • Synthetic
  • Absorbable
  • Osteoconductive
  • Interconnected porosity

TRIHA+® is indicated for the filling of bone gaps or defects that are not intrinsic to the stability of the bone structure.

Example of use:
• Treatment of bone defects (benign tumors or cysts, traumatic lesions)
• Reconstruction during prosthetic revision
• Arthrodesis (foot, ankle, spine, …)
• Filling of osteotomy
• Filling cages
• Spine fusion

Monophasic ceramic 100 % TCP, an ideal answer to bone defects.

SYNTHETIC
• Free from organic phase
• No immunological risk

ABSORBABLE
• Minimum of 2 years

BIOCOMPATIBLE
• Compliant to ISO 10993-1**

**Biological Risk Assessment Report TRIHA+® 096/3/PERB

References

Designation

 References

TRIHA+® 5 cc – 3x3x3 granules

T824402

TRIHA+® 10 cc – 3x3x3 granules

T824405

TRIHA+® 30 cc – 3x3x3 granules

T824415

TRIHA+® 2.5 cc – 5x5x20 sticks (qty: 5)

T827104

TRIHA+® 5 cc – 5x5x20 sticks (qty: 10)

T827105

TRIHA+® 10 cc – Chips 1 – 2 mm

T821210

TRIHA+® 20 cc – Chips 1 – 2 mm

T821220

TRIHA+® 10 cc – Chips 2 – 5 mm

T822510

TRIHA+® 20 cc – Chips 2 – 5 mm

T822520

Bibliography

– « Osseointegration of macroporous calcium phosphate ceramics having a different chemical composition », P. Frayssinet, J.L. Trouillet, N. Rouquet, E. Azimus, A. Autefage, Biomaterials, Vol14, N° 6, 1993
– « Applications cliniques des céramiques phosphocalciques. Résultats cliniques et paracliniques de 66 cas », F. Gouin, M. Cappelli, Cahier d’enseignement de la SOFCOT, N°57, 1996
– « Comparison of calciumhydroxylapatite CEROS 80 et b tricalciumphosphate CEROS 82 in vivo with stable soft tissue interface », V. Geret, W. Mueller, M. Tepic, B.A. Rahn, S.M. Perren, Biomaterials and clinical application, 1987.
– « Intérêt du phosphate tricalcique béta en chirurgie orthopédique et traumatologique des membres. A propos de 56 cas. », Galois L., Mainard D., Delagoutte J.P., Actualités en Biomatériaux, volume V, 2000
– « Céramiques phosphocalciques : influence de leurs caractéristiques sur leur ostéoconductivité. », Frayssinet P., Mathon D., Azimus E., Autefage A., Actualités en Biomatériaux, volume IV, 1998
– « Effect of pH on protein adsorption to hydroxyapatite and tricalcium phosphate ceramics », Sharpe J.R., Sammons R.L., Maquis P.M., Biomaterials, volume 18, 471-476, 1997
– Abstract : « The value of Beta-tricalcium (CERASORB) in pre- prosthetic surgery », Szucs A., Suba Z., Martonffy K., Hrabak K., Gyulai-Gaal S., Dori F., Szabo G., Fogorov Sz, volume 93, 45-52, 2000
– « Ectopic osteogenesis with biphasic ceramics of hydroxyapatite and tricalcium phosphate in rabbits », Kurashina K., Kurita H., Wu Q., Ohtsuka A., Kobayashi H., Biomaterials, volume 23, 407-412, 2002
– « Osteoclastic resorption of calcium phosphate ceramics with different hydroxyapatite / b-tricalcium phosphate ratios », Yamada S., Heymann D., Bouler J.M., Daculsi G., Biomaterials, volume 18, 1037-1041, 1997
– « Morpholigical and biomechanical difference in healing in segmental tibial defects implanted with Biocoral(r) or tricalcium phosphate cylinders », Tie-Ju Gao, Tapio K., Lindholm T., Kommonen B., Biomaterials, volume 18, 219-223, 1997
– « Histomorphometric analysis of tricalcium phosphate ceramic implanted into turkeys », Metsger DS., Arnala I., Faugere MC., Malluche H., Bone, volume 14, 243-248, 1993
– « Marrow cell induced osteogenesis in porous hydroxyapatite and tricalcium phosphate: a comparative histomorphometric study of ectopic bone formation », Ohgushi H., Okamua M., Tamai S., Shors E., Caplan A., Journal of Biomedical Materials Reseach, volume 24, 1563-1570, 1990